My scientific background is in bioanalytics, diagnostics, and instrument design.
Over the years, I’ve contributed to research involving:
- microfluidics and high-precision control systems
- diagnostic instrumentation
- biosensing and analytical methods
- complex system integration
- applied analytical science
My publications reflect this foundation, rigorous, peer-reviewed, and grounded in real-world problems.
Even though this site often explores playful or unusual ideas, my academic work remains the bedrock: the part where precision, discipline, and method meet the real world.
Creativity and scientific rigor aren’t opposites, they feed each other.
These works were carried out at the HES-SO Valais-Wallis in Sion (www.hevs.ch). A warm thanks to all the people I’ve worked with during those years, they are all incredibly talented.
Scientific Contributions
de Gregorio, G. L.; Prim, D.; Zavattoni, A.; Mottini, I.; Pezzoli, D.; Roveda, F.; Pfeifer, M. E.; Segura, J.-M. A Molecularly Imprinted Membrane for High-Density Lipoprotein Extraction in Point-of-Care Testing. Biosensors2025, 15 (10), 685. https://doi.org/10.3390/bios15100685.
Jović, M.; Prim, D.; Paciotti, G.; Pfeifer, M. E. Engineering a Diagnostic Platform Based on a Spatially Resolved Electrochemiluminescence Immunoassay for Low-Plex Biomarker Detection at Point-of-Care: Mild Traumatic Brain Injury and Cardiac Applications. Lab Chip 2025. https://doi.org/10.1039/D5LC00360A.
Jović, M.; Prim, D.; Righini, O.; Tagan, D.; Stäuble, M.; Pignat, M.; Gallay, S.; Geiser, M.; Pfeifer, M. E. A Novel Point-of-Care Diagnostic Prototype System for the Simultaneous Electrochemiluminescent Sensing of Multiple Traumatic Brain Injury Biomarkers. Sens. Diagn. 2023, 2 (4), 964–975. https://doi.org/10.1039/D3SD00090G.
Loussert-Fonta, C.; Stoppini, L.; Neuenschwander, Y.; Righini, O.; Prim, D.; Schmidt, C.; Heuschkel, M. O.; Gomez Baisac, L.; Jovic´, M.; Pfeifer, M. E.; Extermann, J.; Roux, A. Opening the Black Box of Traumatic Brain Injury: A Holistic Approach Combining Human 3D Neural Tissue and an in Vitro Traumatic Brain Injury Induction Device. Frontiers in Neuroscience 2023, 17.
Bojescu, E.-D.; Prim, D.; Pfeifer, M. E.; Segura, J.-M. Fluorescence-Polarization Immunoassays within Glass Fiber Micro-Chambers Enable Tobramycin Quantification in Whole Blood for Therapeutic Drug Monitoring at the Point of Care. Analytica Chimica Acta 2022, 1225, 340240. https://doi.org/10.1016/j.aca.2022.340240.
Jović, M.; Prim, D.; Saini, E.; Pfeifer, M. E. Towards a Point-of-Care (POC) Diagnostic Platform for the Multiplex Electrochemiluminescent (ECL) Sensing of Mild Traumatic Brain Injury (mTBI) Biomarkers. Biosensors 2022, 12 (3), 172. https://doi.org/10.3390/bios12030172.
Taddeo, A.; Prim, D.; Bojescu, E.-D.; Segura, J.-M.; Pfeifer, M. E. Point-of-Care Therapeutic Drug Monitoring for Precision Dosing of Immunosuppressive Drugs. The Journal of Applied Laboratory Medicine 2020, 5 (4), 738–761.https://doi.org/10.1093/jalm/jfaa067.
Kosińska-Cagnazzo, A.; Diering, S.; Prim, D.; Andlauer, W. Identification of Bioaccessible and Uptaken Phenolic Compounds from Strawberry Fruits in in Vitro Digestion/Caco-2 Absorption Model. Food Chemistry 2015, 170, 288–294. https://doi.org/10.1016/j.foodchem.2014.08.070.
Prim, D.; Rebeaud, F.; Cosandey, V.; Marti, R.; Passeraub, P.; Pfeifer, M. E. ADIBO-Based “Click” Chemistry for Diagnostic Peptide Micro-Array Fabrication: Physicochemical and Assay Characteristics. Molecules 2013, 18 (8), 9833–9849. https://doi.org/10.3390/molecules18089833.